Humanized recombinant fibronectin overcoming biomacromolecular transdermal barriers, equipped with patented cell-penetrating peptide technology to deeply anchor integrin receptors, achieving rapid barrier emergency rescue and ECM network reconstruction.
Scientific Illustration
Transdermal Fibronectin - Mechanism & Scientific Evidence
RAW MATERIAL TECHNICAL & REGULATORY DOSSIER
Comprehensive Technical, Quality Specification, and Regulatory Dossier for R&D Formulators, Procurement, and Product Managers
📊
Biotechnology Mechanism & Scientific Evidence
Authoritative Brochure Technical Diagram · Molecular Model · Transdermal & Efficacy Mechanism
Mechanism DiagramTransdermal Fibronectin - Mechanism of Action and Transdermal Delivery Pathway
🔬
Formulation R&D Engineer Guide (R&D Technical Dossier)
Formulation Application · Physicochemical Parameters · Stability & Compatibility
| Standard INCI Name |
Aqua, Recombinant Fibronectin, Butylene Glycol, 1,2-Hexanediol |
CAS Registry No. |
86088-83-7 / 7732-18-5 |
| Recommended Dosage |
1.0% - 5.0% (Recommended 2.0% - 3.0%) |
Optimal pH Range |
6.0 - 7.2 |
| Thermal Processing |
Add below 42°C during gentle mixing phase |
Solubility & Method |
Easily miscible with aqueous phase and hydrogels |
| Appearance & Odor |
Clear colorless liquid, odorless |
Patented Tech / IP |
Humanized Recombinant Fibronectin (RGD sequence >98%) |
💡 Compatibility Guidelines & Precautions: Compatible with non-ionic polymers, hyaluronic acid, and ceramides; avoid strong cationic surfactants
📦
Procurement & Compliance Dossier
NMPA Code · MOQ · Sampling Support · Certificate of Analysis
| NMPA Submission Code |
✓ 008451-01932-7721 |
Supply Packaging |
1kg/fluorinated bottle, 5kg/drum, 25kg/drum |
| Minimum Order Quantity (MOQ) |
1 kg (Ready Stock) |
Delivery Lead Time |
Dispatched within 24-48 hours |
| Storage Conditions |
Store refrigerated at 2-8°C, dark and sealed |
Shelf Life |
24 Months |
| R&D Sample Support |
Complimentary 30g trial sample with formulation recommendations |
Quality Documentation |
Batch COA, SDS, TDS, Cell Migration & Safety Reports |
💡
Product Planning & Marketing Highlights
Core Mechanism · Key Selling Points · Recommended Formats · Scientific Backing
🧬 Core Bio-Tech Barrier & Mechanism of Action:
Contains authentic RGD cell-adhesion motifs that bind integrin alpha5beta1 on epidermal and dermal cells, triggering focal adhesion kinase (FAK) signaling to stimulate keratinocyte migration and rapid wound/barrier healing.
🧴 Recommended Product Formats & Categories:
Barrier rescue ampoules, sensitive skin soothing lotions, post-procedure repair gels, micro-needling serums
📜 Patented Technologies & Scientific Backing:
US and Chinese Invention Patents on Transdermal Recombinant Fibronectin Peptides
⚖️
Regulatory Compliance & Peer-to-Peer Disclaimer
Regulatory & Professional Compliance Statement:
1. The raw material characteristics and experimental data (including cytological studies, mechanism diagrams, and literature citations) presented on this webpage are intended exclusively for technical discussion and formulation R&D reference by cosmetic brand formulators, R&D engineers, product planners, and academic research institutions. They do not constitute finished consumer cosmetic efficacy claims or commercial warranties.
2. Pursuant to the Regulations on the Supervision and Administration of Cosmetics, Standards for Cosmetic Efficacy Claim Evaluation, and relevant global cosmetic regulatory frameworks, cosmetic brand enterprises utilizing this raw material shall be solely responsible for the safety, stability, and efficacy claims of their finished consumer products, and shall independently complete efficacy evaluations and regulatory filings/registrations with the competent health authorities prior to commercial launch. Conclusions from in-vitro or cellular studies shall not be directly extrapolated as consumer claims.
3. Mellgen Biotech assumes no joint or indirect liability for any claims or regulatory non-compliance arising from improper customer formulation, unauthorized off-label claims, or unverified applications.
