Mellgen (Shenzhen) Biotechnology Co., Ltd.
Address: Life Science Industrial Park, Kuichong Sub-district, Dapeng New District, Shenzhen, Guangdong, China
➤ Mellgen (Shenzhen) Biotechnology Co., Ltd.创始人 & 董事长,乾姸国际(香港)科技集团董事长 & 首席科学家;
➤ University of Science and Technology of China (USTC)生物医学工程博士、细胞生物学硕士;
➤ 瑞士苏黎世大学欧亚高级工商管理硕士;
➤ University of Science and Technology of China (USTC)博士后研究员,瑞士苏黎世联邦理工大学访问学者;
➤ 生物技术高级工程师,美国哈佛大学医学院皮肤科学认证专家;
➤ Focusing on AI-empowered synthetic biology new drug R&D and innovative transdermal delivery technologies;
➤ Deeply engaged in the mechanism and applied research of macromolecular drug transdermal delivery;
➤ Proprietary smart fusion system of carrier peptides and active ingredients;
➤ 突破全球药物Transdermal吸收技术瓶颈,多肽Transdermal效率提升十倍;
➤ 申请 50 余项国内外专利,研究成果发表于国际知名权威学术期刊。
1、 Ruan, Renquan; Wen, Longping, et al. Transdermal delivery of human epidermal growth factor facilitated by a peptide chaperon. European Journal of Medicinal Chemistry, 62, pp 405-409, 2013/4.; SCI
2、 Renquan Ruan,Longping
Wen, et al. Recent advances in peptides for enhancing transdermal macromolecular drug delivery. Therapeutic Delivery,2016.1.15,7(2):89~100— 13
3、 Ruan, Renquan; Wen, Longping, et al. Peptide-Chaperone-Directed Transdermal
Protein Delivery Requires Energy. Molecular Pharmaceutics,11(11),pp4015-4022,2014/11.; SCI
4、 Ruan, Renquan; Ding, Weiping, et al. Cell Blebbing upon Addition of Cryoprotectants: A Self-Protection Mechanism. PLos One,
10(4), 2015/4/13.; SCI
5、 Ruan, Renquan; Ding, Weiping, et al. Topical and Targeted Delivery of siRNAs to Melanoma Cells Using a Fusion Peptide Carrier. SCIENTIFIC REPORTS,6 ; SCIE
6、 Ruan, Renquan; Wen, Longping,
et al. Enhanced Transdermal Delivery of Epidermal Growth Factor. Protein and Peptide Letters, 21(6), pp 550-555, 2014/6.; SCI
7、 Ruan, Renquan, Wen, Longping. Theoretical Study on Inhibition of Melanoma with Controlled
,2017.6,45(6):1407~1419;SCIE
8、 Ruan, Renquan; Wen, Longping, et al. Role of the Na+/K+-ATPase BetaSubunit in Peptide-Mediated Transdermal Drug Delivery. Molecular Pharmaceutics, 12(4), pp 1259-1267, 2015/4.; SCI
9、 Ruan, Renquan; Wen, Long-Ping, et al. Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates t. Biomaterials, 73, pp 160-174, 2015/12.;
SCI
10、Renquan Ruan and Jing Liu et al. Development and applications of an in vitro non-alcoholic fatty liver disease model based on 3D-printed liver tissue . International. Journal of Bioprinting



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